Gastroenteropancreatic Neuroendocrine Tumor – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Gastroenteropancreatic Neuroendocrine Tumor Market Outlook

Thelansis’s “Gastroenteropancreatic Neuroendocrine Tumor Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Gastroenteropancreatic Neuroendocrine Tumor treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Gastroenteropancreatic Neuroendocrine Tumor Overview

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs), also known as (carcinoids and Islet cell tumors), Carcinoid tumor are a rare form of neoplastic disease arising from primitive stem cells in the gut wall, particularly in the appendix. They can also be found in other organs, such as the lungs, liver, pancreas, and kidneys. These tumors are of neuroendocrine origin and can secrete humoral factors, including polypeptides, vasoactive amines, and prostaglandins, resulting in a hormonal syndrome. The symptoms of this hormonal syndrome include increased bowel movements, diarrhea, vasoactive flushes (especially of the face), hypotension, tachycardia, venous telangiectasia, dyspnea, and bronchospasms. In addition, the long-term effects of this condition may lead to fibrotic changes in the mesentery, retroperitoneum, and cardiac valves. Carcinoid tumors are classified based on location in the primitive gut that gives rise to the tumor, including foregut, midgut, and hindgut carcinoid tumors. These tumors are further divided into well-differentiated (low and intermediate grade) and poorly differentiated (high grade) categories based on their level of differentiation. The U.S. Food and Drug Administration approved Lutathera (lutetium Lu 177 dotatate) to treat a type of cancer affecting the pancreas or gastrointestinal tract called gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

• Carcinoids are the most common neuroendocrine tumors, with an estimated incidence of 1.5-1.9 cases per 100,000 individuals in the United States.

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2023-2033

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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