Eosinophilic Esophagitis (EoE) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Eosinophilic Esophagitis (EoE) Market Outlook

Thelansis’s “Eosinophilic Esophagitis (EoE) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Eosinophilic Esophagitis treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Eosinophilic Esophagitis (EoE) Overview

Eosinophilic Esophagitis (EoE), also known as the "asthma of the esophagus," is a chronic condition rooted in allergies and immune responses. It shares numerous clinical and pathophysiological features with asthma. This ailment is characterized by inflammation in the esophagus, making it an atopic inflammatory disorder of this organ. Age-related variations in how it manifests have been observed in children and adults. The most frequent initial symptoms in adults include dysphagia, food blockages, heartburn, and chest pain. Strikingly, about 50% of adult patients who initially report food blockages are eventually diagnosed with EoE. In contrast, children tend to exhibit vomiting, heartburn, regurgitation, emesis, and abdominal pain more frequently. Dysphagia and food blockages, typical adult complaints, are rarely seen in younger children but become more common in individuals over 12. The gold standard for diagnosing EoE relies on biopsy results showing increased eosinophils within the esophageal epithelium without concurrent eosinophilic infiltration in the stomach or duodenum. Most EoE patients do not respond well to acid-suppression therapy, and up to 75% of them have a personal or family history of atopic conditions such as asthma, eczema, and rhinitis, as well as allergies to environmental factors or foods.

• In pediatric cases, the most common comorbidities include asthma (13.4%), gastrointestinal disorders of the stomach, duodenum, and intestine (7.26%), allergies (7.01%), and gastroesophageal reflux disease (GERD) (3.69%).

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2023-2033

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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