Forecasting Rare Disease Markets: Why Small Patient Populations Demand a More Rigorous Model
Rare disease markets have an odd commercial paradox built into them: the patient population is tiny, but the market opportunity can still be substantial. That's what makes forecasting them fundamental ...
What’s Driving R&D in Triple-Negative Breast Cancer
For years, chemotherapy was the backbone of triple-negative breast cancer (TNBC) treatment because the disease lacked the molecular targets that transformed treatment in other breast cancer subtypes. ...
Beyond the Static Document: Why Evidence-Driven TPP Optimization Is Becoming a Strategic Imperative in Pharma
Every drug development program starts with a hypothesis about the product it hopes to become. The Target Product Profile (TPP) is where that hypothesis is written down: the intended indication, the ef ...
Trends in HEOR: What Payers and HTA Bodies Are Asking for Now
A therapy can clear every regulatory hurdle and still face difficult questions at the formulary or reimbursement stage. That gap between regulatory approval and patient access is where health economic ...
Primary Market Research in Pharma: Turning Stakeholder Perspectives into Actionable Decisions
In pharma, more data doesn't always mean better answers.Secondary research can tell a team what has happened in a market, such as prescription trends, treatment shares, clinical developments, competit ...
Pharma Launch Forecasting: From Static Annual Models to Real-Time Commercial Intelligence
Background: A global specialty pharmaceutical company was approaching the launch of a new chronic-therapy asset in a market characterized by heavy competition. The compound had strong clinical differ ...
The Evolution of HEOR in Rare Diseases: From Cost-Effectiveness to Strategic Market Access
There used to be a simple rule in pharma: scientists built the drug, clinical teams proved it worked, and health economists showed up near the end to do the math. Run the trial, demonstrate efficacy, ...
A Budget Impact Analysis Payers Can Trust: The Thelansis Framework
How the Thelansis budget impact modeling framework turns a payer's first and most literal question, "What will this cost my budget next year?" into a forecast a client can act on and a payer can indep ...
HER2-Positive Metastatic Breast Cancer: The Treatment Shift Reshaping the Market
A Decade of Reinvention There was a time when a HER2-positive breast cancer diagnosis carried a particularly difficult outlook. The biology was aggressive, treatment options were limited, and metasta ...
Beyond Market Size: How Patient, Epidemiology & Competitive Intelligence Can Shape Oncology Investment Strategies
Background: A biopharmaceutical company was evaluating the investment potential of a targeted oncology asset. Initial market assessments appeared attractive. The indication had a sizable patient popu ...