Squamous Non-Small Cell Lung Cancer (sqNSCLC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034

Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Outlook and Forecast

Squamous Non-Small Cell Lung Cancer (sqNSCLC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034

Published Date : 2024-07-02

Updated On : 2025-01-21

Pages : 158

Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Outlook

Thelansis’s “Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2024 To 2034" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Squamous non-small cell lung cancer treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Squamous Non-Small Cell Lung Cancer (sqNSCLC) Overview

Squamous Non-Small Cell Lung Cancer (sqNSCLC) is a subtype of non-small cell lung cancer, which is one of the two main categories of lung cancer. This particular form originates in the squamous cells, which are flat, thin cells that line the inside of the airways in the lungs. It is often associated with a history of smoking and tends to develop in the central part of the lungs, near the main airways or bronchi. The disease is characterized by its aggressive nature and its tendency to cause symptoms such as persistent coughing, chest pain, shortness of breath, and coughing up blood. As the cancer progresses, it may lead to systemic symptoms like unexplained weight loss, fatigue, and loss of appetite. In advanced stages, sqNSCLC can metastasize, spreading to other parts of the body such as the bones, brain, or liver, which can result in additional complications and symptoms.

Treatment options for sqNSCLC depend on the stage of the disease and may include surgery, chemotherapy, radiation therapy, and targeted therapies. Advances in medical research have led to the development of newer treatments, including immunotherapy, which aims to harness the body's immune system to fight cancer cells. Despite these advancements, the prognosis for sqNSCLC varies widely and is influenced by factors such as the stage at diagnosis, the patient's overall health, and the response to treatment.

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2024-2034

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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Squamous Non-Small Cell Lung Cancer (sqNSCLC) Competitive Landscape

S. no Asset Company Stage
1 BA1302 Shandong Boan Biotechnology Co., Ltd. Phase 1
2 RBN-2397 Ribon Therapeutics, Inc. Phase 1/2
3 JMT101 Shanghai JMT-Bio Inc. Phase 2/3
4 FYB206 Formycon AG Phase 3
5 HS-20117 Hansoh BioMedical R&D Company Phase 2/3
6 ONO-4538 Ono Pharmaceutical Co. Ltd Phase 3
7 Domvanalimab Arcus Biosciences, Inc. Phase 2
8 MB12 mAbxience Research S.L. Phase 3
9 AK112 Injection Summit Therapeutics Phase 3
10 PLB1004 Avistone Biotechnology Co., Ltd. Phase 3

Continued...

KOLs across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

COUNTRY No. Of KOLs
USA 17
GERMANY 4
UK 4
SPAIN 3
FRANCE 2
ITALY 3
JAPAN 3
CHINA 4

 

Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

Data Inputs with sourcing, Market Event, Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast

1.  Squamous Non-Small Cell Lung Cancer (sqNSCLC) – Key Findings Summary

         1.1.    Clinical findings
                     1.1.1. Disease overview
                     1.1.2. Therapeutic practices
                     1.1.3. Future outlook
         1.2.    Commercial findings
                     1.2.1. Squamous Non-Small Cell Lung Cancer (sqNSCLC) market scenario 2024
                     1.2.2. Squamous Non-Small Cell Lung Cancer (sqNSCLC) market scenario 2029
                     1.2.3. Squamous Non-Small Cell Lung Cancer (sqNSCLC) market scenario 2034

2. Squamous Non-Small Cell Lung Cancer (sqNSCLC) Overview

         2.1.    Disease Introduction
         2.2.    Pathophysiology
         2.3.    Signs and Symptoms
         2.4.    Risk Factors
         2.5.    Etiology
         2.6.    Classification
         2.7.    Pathogenesis
         2.8.    Diagnosis
         2.9.    Complications
         2.10. Treatment Algorithm
                     2.10.1.    Treatment in US (guidelines)
                     2.10.2.    Treatment in EU-5 (guidelines)
                     2.10.3.    Treatment in Japan (guidelines)
                     2.10.4.    Treatment in China (guidelines)
         2.11. Treatment Goals for Squamous Non-Small Cell Lung Cancer (sqNSCLC)
         2.12. Referral Patterns
                     2.12.1.    Referral Scenario in US
                     2.12.2.    Referral Scenario in EU-5
                     2.12.3.    Referral Scenario in Japan
                     2.12.4.    Referral Scenario in China
         2.13. Squamous Non-Small Cell Lung Cancer (sqNSCLC) Prognosis
         2.14. Healthcare burden
                     2.14.1.    Healthcare burden in US
                     2.14.2.    Healthcare burden in EU-5
                     2.14.3.    Healthcare burden in Japan
                     2.14.4.    Healthcare burden in China
         2.15.  Unmet Needs in Squamous Non-Small Cell Lung Cancer (sqNSCLC) management
         2.16.  Market Opportunity for Squamous Non-Small Cell Lung Cancer (sqNSCLC)
         2.17. KOL Comments on current and upcoming/expected treatment practices in Squamous Non-Small Cell Lung Cancer (sqNSCLC)

3.       Epidemiology

         3.1.    Epidemiology Overview
         3.2.    Epidemiology by Geography
                     3.2.1. Squamous Non-Small Cell Lung Cancer (sqNSCLC) Epidemiology in US (2024-2034)
                             3.2.1.1.              Incidence of Squamous Non-Small Cell Lung Cancer (sqNSCLC)
                             3.2.1.2.              Diagnosed cases
                             3.2.1.3.              Treatable Patient Pool
                             3.2.1.4.              Epidemiology Trends
                     3.2.2. Squamous Non-Small Cell Lung Cancer (sqNSCLC) Epidemiology in EU-5 (2024-2034)
                             3.2.2.1.              Incidence of Squamous Non-Small Cell Lung Cancer (sqNSCLC)
                             3.2.2.2.              Diagnosed cases
                             3.2.2.3.              Treatable Patient Pool
                             3.2.2.4.              Epidemiology Trends
                     3.2.3. Squamous Non-Small Cell Lung Cancer (sqNSCLC) Epidemiology in Japan (2024-2034)
                             3.2.3.1.              Incidence of Squamous Non-Small Cell Lung Cancer (sqNSCLC)
                             3.2.3.2.              Diagnosed cases
                             3.2.3.3.              Treatable Patient Pool
                             3.2.3.4.              Epidemiology Trends
                     3.2.4. Squamous Non-Small Cell Lung Cancer (sqNSCLC) Epidemiology in China (2024-2034)
                             3.2.4.1.              Incidence of Squamous Non-Small Cell Lung Cancer (sqNSCLC)
                             3.2.4.2.              Diagnosed cases
                             3.2.4.3.              Treatable Patient Pool
                             3.2.4.4.              Epidemiology Trends
         3.3.    Epidemiology Trends (World-wide)

4.       Market Outlook

         4.1.    US Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.1.1. Market Progression (Futuristic)
                     4.1.2. Market Trends and Expectations
                             4.1.2.1.              Worst case scenario
                             4.1.2.2.              Base Case Scenario
                             4.1.2.3.              Best Case Scenario
                     4.1.3. Drivers and Barriers
         4.2.    UK Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.2.1. Market Progression (Futuristic)
                     4.2.2. Market Trends and Expectations
                             4.2.2.1.              Worst case scenario
                             4.2.2.2.              Base Case Scenario
                             4.2.2.3.              Best Case Scenario
                     4.2.3. Drivers and Barriers
         4.3.    France Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.3.1. Market Progression (Futuristic)
                     4.3.2. Market Trends and Expectations
                             4.3.2.1.              Worst case scenario
                             4.3.2.2.              Base Case Scenario
                             4.3.2.3.              Best Case Scenario
                     4.3.3. Drivers and Barriers
         4.4.    Germany Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.4.1. Market Progression (Futuristic)
                     4.4.2. Market Trends and Expectations
                             4.4.2.1.              Worst case scenario
                             4.4.2.2.              Base Case Scenario
                             4.4.2.3.              Best Case Scenario
                     4.4.3. Drivers and Barriers
         4.5.    Italy Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.5.1. Market Progression (Futuristic)
                     4.5.2. Market Trends and Expectations
                             4.5.2.1.              Worst case scenario
                             4.5.2.2.              Base Case Scenario
                             4.5.2.3.              Best Case Scenario
                     4.5.3. Drivers and Barriers
         4.6.    Spain Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.6.1. Market Progression (Futuristic)
                     4.6.2. Market Trends and Expectations
                             4.6.2.1.              Worst case scenario
                             4.6.2.2.              Base Case Scenario
                             4.6.2.3.              Best Case Scenario
                     4.6.3. Drivers and Barriers
         4.7.    Japan Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.7.1. Market Progression (Futuristic)
                     4.7.2. Market Trends and Expectations
                             4.7.2.1.              Worst case scenario
                             4.7.2.2.              Base Case Scenario
                             4.7.2.3.              Best Case Scenario
                     4.7.3. Drivers and Barriers
         4.8.    China Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market Forecast 2024-2034
                     4.8.1. Market Progression (Futuristic)
                     4.8.2. Market Trends and Expectations
                             4.8.2.1.              Worst case scenario
                             4.8.2.2.              Base Case Scenario
                             4.8.2.3.              Best Case Scenario
                     4.8.3. Drivers and Barriers
         4.9.    Key Expected Milestones (world-wide) Impacting the Market

5.       Competitive Landscape

         5.1.    Pipeline Therapies Overview
                     5.1.1. Phase III Therapies
                                      5.1.1.1.                     Current Status
                                      5.1.1.2.                     Trial details, results
                                      5.1.1.3.                     Approval Timeline
                                      5.1.1.4.                     Likelihood of approval
                                      5.1.1.5.                     Expected Product Positioning
                             5.1.1.2.              All other Phase III Therapies …..
                             5.1.1.3.              Attribute Analysis of Phase III molecules
                     5.1.2.  Phase II and Phase I/II Therapies
                                      5.1.2.1.                     Current Status
                                      5.1.2.2.                     Trial details, results
                                      5.1.2.3.                     Approval Timelines
                     5.1.3. List of active Pre-clinical Therapies
                                      5.1.3.1.                     Status in Squamous Non-Small Cell Lung Cancer (sqNSCLC)
                                      5.1.3.2.                     Company positioning
                             5.1.3.2.              All other pre-clinical therapies
                     5.1.4. List of Inactive/discontinued assets
                             5.1.4.1.              Business impact of discontinuations on current pipeline
                     5.1.5. Potential winners from Squamous Non-Small Cell Lung Cancer (sqNSCLC) Pipeline
                             5.1.5.1.              Potential Blockbusters across the pipeline

6.       Regulatory/Approval Scenario

         6.1.    Regulatory/Approval Framework in US
                     6.1.1. Policy Framework
                     6.1.2. Payer Expectations
         6.2.    Regulatory/Approval Framework in UK
                     6.2.1. Policy Framework
                     6.2.2. Payer Expectations
         6.3.    Regulatory/Approval Framework in France
                     6.3.1. Policy Framework
                     6.3.2. Payer Expectations
         6.4.    Regulatory/Approval Framework in Germany
                     6.4.1. Policy Framework
                     6.4.2. Payer Expectations
         6.5.    Regulatory/Approval Framework in Italy
                     6.5.1. Policy Framework
                     6.5.2. Payer Expectations
         6.6.    Regulatory/Approval Framework in Spain
                     6.6.1. Policy Framework
                     6.6.2. Payer Expectations
         6.7.       Regulatory/Approval Framework in Japan
                     6.7.1. Policy Framework
                     6.7.2. Payer Expectations
         6.8.       Regulatory/Approval Framework in China
                     6.8.1. Policy Framework
                     6.8.2. Payer Expectations

7.       Clinical Trial Assessment – Current and Future Paradigm

         7.1.    Distribution of Primary Endpoints across trials
         7.2.    Distribution of Secondary Endpoints across trials
         7.3.    Evolution and acceptance of surrogate endpoints
         7.4.    Key Investigator initiated trials
         7.5.    Attrition analysis
                     7.5.1. Suspended/Discontinued Assets
                     7.5.2. Failed Trials, Reasons and Business Impact
                     7.5.3. Terminated Trials, Reasons and Business Impact
                     7.5.4. Withdrawn Trials, Reasons and Business Impact
         7.6.    Trial enrollment scenario and challenges
         7.7.    Clinical Trial Guidance (across geographies)

8.       Thelansis Commentary

         8.1.    Key Unmet needs in Squamous Non-Small Cell Lung Cancer (sqNSCLC)
         8.2.    Possible Best-case Clinical Trial Strategies
         8.3.    Possible Best Case Targeted Product Profile (TPP)
         8.4.    Possible Best-case Market positioning strategies
         8.5.    Possible Best-case Market Access Strategies
         8.6.    Possible Best-case LCM Strategies
         8.7.    Overall View on Squamous Non-Small Cell Lung Cancer (sqNSCLC) Market in Dollar Value

9.       Report Methodology

         9.1.    Secondary research
         9.2.    Primary research
         9.3.    Data collation
         9.4.    Insight Generation

10.   About Thelansis

         10.1.    Our Capabilities
         10.2.    Our Services
         10.3.    Our Contacts
         10.4.    Disclaimer