Respiratory Virus Infection (RVI) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032

Respiratory Virus Infection (RVI) Market Outlook and Forecast

Respiratory Virus Infection (RVI) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032

Published Date : 2022-08-06

Updated On : 2023-07-11

Pages : 163

Respiratory Virus Infection (RVI) Market Outlook

Thelansis’s “Respiratory Virus Infection (RVI) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Respiratory Virus Infection treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Respiratory Virus Infection (RVI) Overview

Respiratory virus infections primarily affect the respiratory tract, including the nose, throat, airways, and lungs. Various types of viruses can cause these infections and range in severity from mild, common cold-like symptoms to more severe respiratory illnesses. Here are some common examples of respiratory viruses: 

  1. Influenza Virus: The flu is caused by influenza viruses and typically results in symptoms like fever, sore throat, cough, chills, runny or stuffy nose, muscle or body aches, fatigue, and headaches. In severe cases, the flu can lead to pneumonia or other complications, especially in vulnerable populations.
  2. Rhinovirus: Rhinoviruses are the most common cause of the common cold. Symptoms include a runny or stuffy nose, sneezing, coughing, sore throat, and mild body aches. Rhinovirus infections are usually mild and self-limiting.
  3. Coronaviruses: Coronaviruses can cause various respiratory illnesses, from mild colds to more severe diseases like COVID-19. COVID-19, caused by the SARS-CoV-2 virus, was declared a pandemic in 2020 and has had a significant global impact, leading to widespread illness and mortality.
  4. Respiratory Syncytial Virus (RSV): RSV primarily affects infants and young children. It can cause symptoms similar to the common cold, such as runny nose, fever, and cough. In severe cases, RSV can lead to bronchiolitis or pneumonia, especially in infants and older adults.
  5. Adenoviruses: Adenoviruses can cause various respiratory symptoms, including cold-like symptoms, sore throat, and bronchitis. In some cases, they can also lead to more severe respiratory illnesses and pneumonia.
  6. Parainfluenza Virus: Parainfluenza viruses can cause croup, which leads to a barking cough and noisy breathing. They can also cause cold-like symptoms and bronchitis.
  7. Metapneumovirus: This virus can cause symptoms similar to RSV, including cold-like symptoms and more severe lower respiratory tract infections.
  8. Enteroviruses: While primarily gastrointestinal viruses, certain enteroviruses can also cause respiratory symptoms, including cough and cold symptoms.

Viral infections typically target either the upper or lower respiratory tract. While categorization based on the responsible virus (like influenza) is possible, a more common clinical classification revolves around the syndrome displayed (such as the common cold, bronchiolitis, croup, or pneumonia). While particular pathogens tend to exhibit distinct clinical signs (like rhinovirus being linked to common cold symptoms and RSV often causing bronchiolitis), each virus has the potential to trigger various respiratory syndromes. The severity of viral respiratory ailments varies greatly, with more severe cases being more likely in older adults and infants. Respiratory viruses are divided into three groups based on their seasonal outbreaks. Influenza virus, human coronaviruses (like OC43, HKU1, 229E, and NL63 strains), and human respiratory syncytial virus (RSV) exhibit peaks during the winter (termed winter viruses). Adenovirus, human bocavirus (HBoV), parainfluenza virus (PIV), human metapneumovirus (hMPV), and rhinovirus can be detected throughout the year (referred to as all-year viruses).

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2022-2032

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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Respiratory Virus Infection (RVI) Competitive Landscape

S. no Asset Company Stage
1 Raphamin Materia Medica Holding Phase 3
2 Ingavirin® Valenta Pharm JSC Phase 3
3 Enisamium Iodide Joint Stock Company "Farmak" Phase 3
4 RESP301 Thirty Respiratory Limited Phase 3
5 Nirsevimab Sanofi Pasteur, a Sanofi Company Phase 3
6 RSVPreF3 OA vaccine GlaxoSmithKline Phase 3
7 Tozorakimab AstraZeneca Phase 3
8 AK0529 Ark Biosciences Inc. Phase 3
9 mRNA-1345 ModernaTX, Inc. Phase 3
10 XC221 Pharmenterprises LLC Phase 2

Continued...

KOLs across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.

COUNTRY No. Of KOLs
USA 17
GERMANY 4
UK 4
SPAIN 3
FRANCE 2
ITALY 3
JAPAN 3
CHINA 4

Respiratory Virus Infection (RVI) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

Data Inputs with sourcing, Market Event, Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.

Respiratory Virus Infection (RVI) Market Forecast

 

1.  Respiratory Virus Infection (RVI) – Key Findings Summary

         1.1.    Clinical findings
                     1.1.1. Disease overview
                     1.1.2. Therapeutic practices
                     1.1.3. Future outlook
         1.2.    Commercial findings
                     1.2.1. Respiratory Virus Infection (RVI) market scenario 2022
                     1.2.2. Respiratory Virus Infection (RVI) market scenario 2025
                     1.2.3. Respiratory Virus Infection (RVI) market scenario 2032

2. Respiratory Virus Infection (RVI) Overview

         2.1.    Disease Introduction
         2.2.    Pathophysiology
         2.3.    Signs and Symptoms
         2.4.    Risk Factors
         2.5.    Etiology
         2.6.    Classification
         2.7.    Pathogenesis
         2.8.    Diagnosis
         2.9.    Complications
         2.10. Treatment Algorithm
                     2.10.1.    Treatment in US (guidelines)
                     2.10.2.    Treatment in EU-5 (guidelines)
                     2.10.3.    Treatment in Japan (guidelines)
                     2.10.4.    Treatment in China (guidelines)
         2.11. Treatment Goals for Respiratory Virus Infection (RVI)
         2.12. Referral Patterns
                     2.12.1.    Referral Scenario in US
                     2.12.2.    Referral Scenario in EU-5
                     2.12.3.    Referral Scenario in Japan
                     2.12.4.    Referral Scenario in China
         2.13. Respiratory Virus Infection (RVI) Prognosis
         2.14. Healthcare burden
                     2.14.1.    Healthcare burden in US
                     2.14.2.    Healthcare burden in EU-5
                     2.14.3.    Healthcare burden in Japan
                     2.14.4.    Healthcare burden in China
         2.15.  Unmet Needs in Respiratory Virus Infection (RVI) management
         2.16.  Market Opportunity for Respiratory Virus Infection (RVI)
         2.17. KOL Comments on current and upcoming/expected treatment practices in Respiratory Virus Infection (RVI)

3.       Epidemiology

         3.1.    Epidemiology Overview
         3.2.    Epidemiology by Geography
                     3.2.1. Respiratory Virus Infection (RVI) Epidemiology in US (2022-2032)
                             3.2.1.1.              Incidence of Respiratory Virus Infection (RVI)
                             3.2.1.2.              Diagnosed cases
                             3.2.1.3.              Treatable Patient Pool
                             3.2.1.4.              Epidemiology Trends
                     3.2.2. Respiratory Virus Infection (RVI) Epidemiology in EU-5 (2022-2032)
                             3.2.2.1.              Incidence of Respiratory Virus Infection (RVI)
                             3.2.2.2.              Diagnosed cases
                             3.2.2.3.              Treatable Patient Pool
                             3.2.2.4.              Epidemiology Trends
                     3.2.3. Respiratory Virus Infection (RVI) Epidemiology in Japan (2022-2032)
                             3.2.3.1.              Incidence of Respiratory Virus Infection (RVI)
                             3.2.3.2.              Diagnosed cases
                             3.2.3.3.              Treatable Patient Pool
                             3.2.3.4.              Epidemiology Trends
                     3.2.4. Respiratory Virus Infection (RVI) Epidemiology in China (2022-2032)
                             3.2.4.1.              Incidence of Respiratory Virus Infection (RVI)
                             3.2.4.2.              Diagnosed cases
                             3.2.4.3.              Treatable Patient Pool
                             3.2.4.4.              Epidemiology Trends
         3.3.    Epidemiology Trends (World-wide)

4.       Market Outlook

         4.1.    US Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.1.1. Market Progression (Futuristic)
                     4.1.2. Market Trends and Expectations
                             4.1.2.1.              Worst case scenario
                             4.1.2.2.              Base Case Scenario
                             4.1.2.3.              Best Case Scenario
                     4.1.3. Drivers and Barriers
         4.2.    UK Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.2.1. Market Progression (Futuristic)
                     4.2.2. Market Trends and Expectations
                             4.2.2.1.              Worst case scenario
                             4.2.2.2.              Base Case Scenario
                             4.2.2.3.              Best Case Scenario
                     4.2.3. Drivers and Barriers
         4.3.    France Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.3.1. Market Progression (Futuristic)
                     4.3.2. Market Trends and Expectations
                             4.3.2.1.              Worst case scenario
                             4.3.2.2.              Base Case Scenario
                             4.3.2.3.              Best Case Scenario
                     4.3.3. Drivers and Barriers
         4.4.    Germany Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.4.1. Market Progression (Futuristic)
                     4.4.2. Market Trends and Expectations
                             4.4.2.1.              Worst case scenario
                             4.4.2.2.              Base Case Scenario
                             4.4.2.3.              Best Case Scenario
                     4.4.3. Drivers and Barriers
         4.5.    Italy Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.5.1. Market Progression (Futuristic)
                     4.5.2. Market Trends and Expectations
                             4.5.2.1.              Worst case scenario
                             4.5.2.2.              Base Case Scenario
                             4.5.2.3.              Best Case Scenario
                     4.5.3. Drivers and Barriers
         4.6.    Spain Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.6.1. Market Progression (Futuristic)
                     4.6.2. Market Trends and Expectations
                             4.6.2.1.              Worst case scenario
                             4.6.2.2.              Base Case Scenario
                             4.6.2.3.              Best Case Scenario
                     4.6.3. Drivers and Barriers
         4.7.    Japan Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.7.1. Market Progression (Futuristic)
                     4.7.2. Market Trends and Expectations
                             4.7.2.1.              Worst case scenario
                             4.7.2.2.              Base Case Scenario
                             4.7.2.3.              Best Case Scenario
                     4.7.3. Drivers and Barriers
         4.8.    China Respiratory Virus Infection (RVI) Market Forecast 2022-2032
                     4.8.1. Market Progression (Futuristic)
                     4.8.2. Market Trends and Expectations
                             4.8.2.1.              Worst case scenario
                             4.8.2.2.              Base Case Scenario
                             4.8.2.3.              Best Case Scenario
                     4.8.3. Drivers and Barriers
         4.9.    Key Expected Milestones (world-wide) Impacting the Market

5.       Competitive Landscape

         5.1.    Pipeline Therapies Overview
                     5.1.1. Phase III Therapies
                                      5.1.1.1.                     Current Status
                                      5.1.1.2.                     Trial details, results
                                      5.1.1.3.                     Approval Timeline
                                      5.1.1.4.                     Likelihood of approval
                                      5.1.1.5.                     Expected Product Positioning
                             5.1.1.2.              All other Phase III Therapies …..
                             5.1.1.3.              Attribute Analysis of Phase III molecules
                     5.1.2.  Phase II and Phase I/II Therapies
                                      5.1.2.1.                     Current Status
                                      5.1.2.2.                     Trial details, results
                                      5.1.2.3.                     Approval Timelines
                     5.1.3. List of active Pre-clinical Therapies
                                      5.1.3.1.                     Status in Respiratory Virus Infection (RVI)
                                      5.1.3.2.                     Company positioning
                             5.1.3.2.              All other pre-clinical therapies
                     5.1.4. List of Inactive/discontinued assets
                             5.1.4.1.              Business impact of discontinuations on current pipeline
                     5.1.5. Potential winners from Respiratory Virus Infection (RVI) Pipeline
                             5.1.5.1.              Potential Blockbusters across the pipeline

6.       Regulatory/Approval Scenario

         6.1.    Regulatory/Approval Framework in US
                     6.1.1. Policy Framework
                     6.1.2. Payer Expectations
         6.2.    Regulatory/Approval Framework in UK
                     6.2.1. Policy Framework
                     6.2.2. Payer Expectations
         6.3.    Regulatory/Approval Framework in France
                     6.3.1. Policy Framework
                     6.3.2. Payer Expectations
         6.4.    Regulatory/Approval Framework in Germany
                     6.4.1. Policy Framework
                     6.4.2. Payer Expectations
         6.5.    Regulatory/Approval Framework in Italy
                     6.5.1. Policy Framework
                     6.5.2. Payer Expectations
         6.6.    Regulatory/Approval Framework in Spain
                     6.6.1. Policy Framework
                     6.6.2. Payer Expectations
         6.7.       Regulatory/Approval Framework in Japan
                     6.7.1. Policy Framework
                     6.7.2. Payer Expectations
         6.8.       Regulatory/Approval Framework in China
                     6.8.1. Policy Framework
                     6.8.2. Payer Expectations

7.       Clinical Trial Assessment – Current and Future Paradigm

         7.1.    Distribution of Primary Endpoints across trials
         7.2.    Distribution of Secondary Endpoints across trials
         7.3.    Evolution and acceptance of surrogate endpoints
         7.4.    Key Investigator initiated trials
         7.5.    Attrition analysis
                     7.5.1. Suspended/Discontinued Assets
                     7.5.2. Failed Trials, Reasons and Business Impact
                     7.5.3. Terminated Trials, Reasons and Business Impact
                     7.5.4. Withdrawn Trials, Reasons and Business Impact
         7.6.    Trial enrollment scenario and challenges
         7.7.    Clinical Trial Guidance (across geographies)

8.       Thelansis Commentary

         8.1.    Key Unmet needs in Respiratory Virus Infection (RVI)
         8.2.    Possible Best-case Clinical Trial Strategies
         8.3.    Possible Best Case Targeted Product Profile (TPP)
         8.4.    Possible Best-case Market positioning strategies
         8.5.    Possible Best-case Market Access Strategies
         8.6.    Possible Best-case LCM Strategies
         8.7.    Overall View on Respiratory Virus Infection (RVI) Market in Dollar Value

9.       Report Methodology

         9.1.    Secondary research
         9.2.    Primary research
         9.3.    Data collation
         9.4.    Insight Generation

10.   About Thelansis

         10.1.    Our Capabilities
         10.2.    Our Services
         10.3.    Our Contacts
         10.4.    Disclaimer