Preeclampsia – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032

Preeclampsia Market Outlook

Thelansis’s “Preeclampsia Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Preeclampsia treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Preeclampsia Overview

Preeclampsia is a condition characterized by high blood pressure during pregnancy. The criteria for identifying preeclampsia initially involve a systolic blood pressure of 140 mm Hg or higher or a diastolic blood pressure of 90 mm Hg or higher, recorded on at least two occasions at least 4 hours apart. Alternatively, if the time interval is shorter, the criteria are a systolic blood pressure of 160 mm Hg or higher or a diastolic blood pressure of 110 mm Hg or higher. All of these measurements must be made after 20 weeks of gestation. While there is a comprehensive understanding of how preeclampsia is clinically presented, diagnosed, and managed as part of routine practice, the underlying causes remain unclear. A prevalent explanation for preeclampsia involves abnormal placentation, which triggers significant dysfunction in the mother's body. Despite challenges, abnormal placentation remains a well-supported cause of preeclampsia, leading to unusual remodeling of spiral arteries, placental ischemia, hypoxia, and oxidative stress. Conditions that share symptoms with preeclampsia can also inadvertently increase the risk of developing it. These include chronic hypertension, gestational hypertension, antiphospholipid antibody syndrome, thrombotic microangiopathies, lupus, epilepsy, or seizure disorders. In preeclamptic patients, delaying the delivery of the fetus during the late preterm phase raises the likelihood of severe hypertension. This, in turn, can result in serious complications like eclampsia, HELLP syndrome, pulmonary edema, myocardial infarction, acute respiratory distress syndrome, stroke, renal and retinal damage, and fetal issues such as growth restrictions, placental abruption, and fetal or maternal death. The management of preeclampsia begins with early diagnosis and intervention, focusing on maintaining appropriate blood pressure levels and preventing seizures. Blood pressure control can be accomplished by using medications like beta-blockers (e.g., labetalol) or calcium channel blockers (e.g., nifedipine).

• Preeclampsia is responsible for approximately 10 to 15 percent of maternal fatalities across the globe.

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2022-2032

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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