Malignant Mesothelioma – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032

Malignant Mesothelioma Market Outlook

Thelansis’s “Malignant Mesothelioma Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Malignant Mesothelioma treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Malignant Mesothelioma Overview

Malignant mesothelioma is a rare form of cancer arising from the mesothelial cells that line various viscera. It is primarily associated with asbestos exposure and is observed in the pleural lining (malignant pleural mesothelioma). The exact mechanisms by which asbestos exposure leads to the development of malignant mesothelioma are not fully understood but are believed to involve repeated pleural inflammation, interference with cell division, activation of proto-oncogenes, and oxidative stress. The three histological subtypes of mesothelioma are epithelioid, sarcomatoid, and mixed, with the epithelioid subtype associated with a better prognosis. Malignant pleural mesothelioma spreads locally, initially affecting the parietal pleura and then spreading to the visceral pleura, chest wall, diaphragm, or mediastinum. Direct invasion of regional lymph nodes, particularly the bronchopulmonary or hilar nodes, is also observed. The initial symptoms of malignant pleural mesothelioma are usually vague and atypical, including abdominal pain, distension, weight loss, anorexia, and ascites. The differential diagnosis for this condition includes several other lung cancers, benign pleural masses, and lung infections. Multiple factors, including the presentation stage, gender, and the extent of surgical resection, influence the prognosis of malignant pleural mesothelioma. Patients who underwent successful surgical resection have a significantly better prognosis, with longer median survival and higher 5-year survival rates.

• In the USA, the overall prevalence of malignant mesothelioma is estimated to be 1-2 cases per million annually.

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2022-2032

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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