Chronic kidney Disease (CKD) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Chronic kidney Disease (CKD) Market Outlook

Thelansis’s “Chronic kidney Disease (CKD) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Chronic kidney Disease treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Chronic kidney Disease (CKD) Overview

Chronic kidney disease (CKD) is characterized by kidney damage lasting over three months, indicated by abnormal albumin excretion or decreased kidney function as measured by glomerular filtration rate (GFR). Diabetes and high blood pressure are its primary causes. In children, CKD typically results from structural anomalies or inherited conditions like polycystic kidney disease. CKD is categorized into five stages based on GFR test results. As the stages progress, kidney function declines. Slowing down kidney damage is crucial at each stage. Screening for CKD involves two standard tests: GFR and urine albumin. Metformin is the preferred treatment for type 2 diabetes with CKD, usually starting with an eGFR above 45 mL/min/1.73 m2 and continuing safely until it drops to 30 mL/min/1.73 m2. Sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists can reduce CKD progression. SGLT-2 inhibitors may slow CKD progression and reduce heart failure-related hospitalizations, though their effect on mortality is uncertain. CKD can affect multiple body systems, leading to fluid retention, swelling, high blood pressure, pulmonary edema, hyperkalemia, anemia, and heart disease.

• Approximately 14% of US adults, roughly 35.5 million people, have CKD, with women slightly more affected than men (15.93% vs. 13.52%).

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2023-2033

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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