Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) Market Outlook

Thelansis’s “Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Acute Bacterial Skin and Skin Structure Infections treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).

Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) Overview

Acute bacterial skin and skin structure infections (ABSSSIs) commonly prompt visits to acute healthcare facilities, including emergency departments. Staphylococcus aureus stands out as the primary culprit behind these infections, with the rise of community-associated methicillin-resistant Staphylococcus aureus (MRSA) posing significant challenges in treatment. In addressing ABSSSIs, various medications such as dalbavancin, oritavancin, tedizolid, and delafloxacin are employed. The guidelines classify ABSSSIs into purulent and nonpurulent types, distinguishing cellulitis and erysipelas as nonpurulent and abscesses as purulent. Treatment recommendations vary accordingly, with medications like vancomycin, linezolid, tigecycline, daptomycin, ceftaroline, and telavancin reserved for severe purulent infections, while trimethoprim-sulfamethoxazole and doxycycline are suggested for moderate cases. For infections caused by methicillin-susceptible S. aureus (MSSA), cefazolin and clindamycin are advised for severe cases, and dicloxacillin and cephalexin for moderate ones. The location of the wound plays a pivotal role in its etiology in wound infections. Gram-negative bacteria or anaerobes, alongside Gram-positive bacteria, may be responsible. For instance, Gram-negative bacteria are often the culprits in perianal or lower abdominal wound infections, whereas MRSA and MSSA predominate in infections following cardiothoracic surgery, potentially leading to severe complications like endocarditis, bacteremia, or nosocomial pneumonia. Research indicates that around 20–25% of patients receive inappropriate antibiotic treatment, potentially prolonging their hospitalization and heightening the risk of morbidity and mortality.

Geography Covered:

North America- the United States and Canada

Europe- EU5 (Germany, France, Italy, Spain, and the United Kingdom)

Other countries- Japan & China

Study Period: 2023-2033

Current Clinical Practice and Treatment Algorithm

This section of the study covers country-specific current clinical practice, the standard of care, and significant limitations around addressing the unmet needs. Retrospective analysis and bench-marking of clinical study outcomes are presented in terms of Pre-treatment & post-treatment clinical and demographic patient characteristics. Essentially, this section will cover the evolution of the current competitive landscape and its impact on the future treatment paradigm.

KOL Insights:

KOLs across 8 MM markets from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs

Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard)

- Data Inputs with sourcing

- Market Event and Product Event

- Country-specific Forecast Model

- Market uptake and patient share uptake

- Attribute Analysis

- Analog Analysis

- Disease burden and pricing scenario

- Summary and Insights

NPV/ IRR Calculator-

Optimization of cash flow/ revenue flow concerning all fixed and variable investments throughout the product development process. The rate of return on an investment is a critical indicator to ensure the profitability and break-even of the project.

Competitive Landscape:

The competitive landscape includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review such as Orphan drug designation, Fast track, Priority Review, Breakthrough Therapy Designation, Rare Pediatric Disease Designation, and Accelerated Approval are tracked and supplemented with analyst commentary.

Clinical Trial Assessment-

Detailed clinical trial data analysis and critical product positioning include trial design, primary outcomes, secondary outcomes, dosing and schedules, inclusion and exclusion criteria, recruitment status and essentially covers the reported adverse events. Majorly the trial analysis helps determine the potential of the critical assets and their probable filing and launch date.

Unmet Medical Needs Overview-

This report presents the most important clinical unmet needs in the treatment, according to Thelansis research and analysis. Other essential unmet needs identified through our study include decreased cost burden on patients, improved administration convenience, and improved patient compliance.

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